Two of the top five seeds look to set up a blockbuster semifinal by continuing their dominance over quarterfinal opponents.
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Rafael Nadal battled past Philipp Kohlschreiber in four sets to reach the US Open quarterfinals.
Spanish veteran Tommy Robredo stunned 17-time major champion Roger Federer on Louis Armstrong Stadium.
US Open Fast Forward breaks down every match on a busy Monday with Round of 16 action in both singles draws.
A surging Novak Djokovic dropped just four games under the lights of Arthur Ashe.
World No. 1 Serena Williams avenged her Australian Open to Sloane Stephens, reaching the US Open quarterfinals.
The second week begins for the women, while the first week concludes for the men.
For the second straight US Open, the streaky Philipp Kohlschreiber outlasted top American John Isner.
Saturday decides the remaining matchups in the final 16 of the US Open women’s draw.
In a four-hour battle of former US Open champions, Lleyton Hewitt upset world No. 6 Juan Martin Del Potro.